As of March 2025, certain staples remain dominant, while newer varieties are making waves in dispensaries across the country. Drawing from data provided by state regulatory agencies, the strain review site Leafly, and our readers, this updated list highlights the most sought-after marijuana strains currently captivating users nationwide as of March 2025.
Blue Dream
A sativa-dominant hybrid that’s remained popularity for decades, Blue Dream continues to be a top choice among cannabis enthusiasts, retaining its top spots after months of Runtz being the most popular strain. Known for its sweet berry aroma and balanced effects, it offers an uplifting cerebral buzz followed by gentle full-body relaxation, making it suitable for both novice and seasoned users.
Lemon Cherry Gelato
This hybrid strain has surged in popularity, particularly in markets like New York and California. Celebrated for its vibrant flavor profile—a blend of citrus, berry, and sweet tropical notes—it delivers euphoric and relaxing effects, making it a favorite among consumers seeking both flavor and potency.
Apple Fritter
Combining sweet apple flavors with a euphoric and relaxing high, Apple Fritter remains a popular choice. It’s perfect for those seeking pain relief without sedation, allowing users to stay functional while enjoying its stress-reducing effects.
Permanent Marker
A newer strain that has quickly gained traction, Permanent Marker features a strong, distinct aroma reminiscent of fresh ink with floral and gas-like undertones. This hybrid delivers a mix of cerebral euphoria and body relaxation, making it a favorite among seasoned consumers.
Sour Diesel
A classic sativa-dominant strain, Sour Diesel is renowned for its pungent, fuel-like aroma and energizing effects. It’s favored by users seeking to alleviate stress and fatigue while maintaining motivation and focus.
Gelato
This hybrid remains a crowd-pleaser due to its dessert-like flavor and well-balanced effects. Gelato provides a euphoric yet soothing experience, making it ideal for unwinding without feeling too sedated.
Wedding Cake
Known for its calming and euphoric effects, Wedding Cake offers a luxurious flavor profile that positions it as one of the best weed strains in California and a standout among emerging cannabis favorites.
Runtz
This hybrid, a cross between Zkittlez and Gelato, remains a popular choice, although it appears to have been surpassed in popularity in recent months by a few other strains. Still, the strain remains a great choice for those seeking a euphoric boost followed by a calming body relaxation.
Zoap
Zoap is a hybrid resulting from the cross of (OG Kush x Z) x Sherbert. It offers a unique flavor profile with chemical lye notes complemented by apricot and apple undertones. Users report a relaxed and calming high, making it suitable for social settings. Users also note its benefits as an appetite stimulation.
Cap Junky
Cap Junky is a cross between Alien Cookies and Kush Mints #11. Known for its dense, resin-coated buds, it delivers strong effects described as hitting “right between the eyes, deep in the head.” The aroma is a complex blend, with some users noting scents of mango yogurt, apricot, apple, and mint.
RS-11 (Rainbow Sherbert #11)
Gaining traction in early 2025, RS-11 is a hybrid strain known for its tropical flavors reminiscent of peach and citrus. Users report effects that are focused and relaxed, making it suitable for creative endeavors and social interactions.
H/T: www.newsbreak.com
