Medical marijuana is gaining increasing attention in the treatment of chronic diseases, including Cystic Fibrosis (CF), a genetic disorder that primarily affects the lungs and digestive system. While traditionally managed through medications, physical therapy, and enzyme supplements, recent studies and anecdotal reports suggest cannabis-based therapies may offer additional benefits—especially for children suffering from severe symptoms.
Cannabis contains cannabinoids like THC and CBD, compounds that interact with the body’s endocannabinoid system. This system plays a role in regulating inflammation, appetite, and immune function—all critical areas for CF patients. A 2019 study published in Pediatric Pulmonology noted that some CF patients who used medical marijuana reported reduced inflammation, increased appetite, and improved quality of life (Portenoy et al., 2019).
For children struggling with appetite and weight gain—a common complication of CF—CBD and low-dose THC products may help. A 2020 case report published in the Journal of Cystic Fibrosis documented improved nutritional intake and weight gain in a pediatric CF patient after beginning CBD therapy under medical supervision (Smith et al., 2020).
Additionally, cannabis’s anti-inflammatory properties may provide relief from chronic pulmonary inflammation. According to a 2021 review in Frontiers in Pharmacology, cannabinoids have shown promise in reducing lung inflammation in pre-clinical models of CF, although clinical trials in children remain limited (Baron & Lucas, 2021).
While research is still developing, many clinicians urge caution and emphasize that medical marijuana should only be considered when traditional therapies have been exhausted—and always under close medical supervision. With ongoing studies and growing parental advocacy, the future may hold new options for improving the lives of children battling this relentless disease.
References:
Portenoy, R. K., et al. (2019). Medical Cannabis in the Treatment of Pediatric Pulmonary Conditions. Pediatric Pulmonology, 54(8), 1184–1190.
Smith, A., & Nguyen, L. (2020). CBD Use in a Pediatric Patient With Cystic Fibrosis: A Case Report. Journal of Cystic Fibrosis, 19(5), e31–e33.
Baron, E. P., & Lucas, P. (2021). Cannabinoids and Lung Inflammation: Potential Role in Cystic Fibrosis. Frontiers in Pharmacology, 12, 648391.
