Sign me up! FLANDREAU, S.D. (AP) — The Santee Sioux tribe has already proven its business acumen, running a successful casino, a 120-room hotel and a 240-head buffalo ranch on the plains of South Dakota. But those enterprises have not been immune to competition and the lingering effects of the Great Recession, so the small tribe of 400 is undertaking a new venture — … [Read more...] about South Dakota tribe to open nation’s 1st marijuana resort